Beta-adrenergic drug, produces arterial and arteriolar vasodilation at the peripheral and cerebral level; It also causes an increase in cardiac frequency and output, consequently the mean arterial pressure does not change .

Therapeutic indications

Peripheral vascular disease (such as obliterative arteriosclerosis, obliterative thromboangiitis, diabetic vasculopathy, Enf. And Raynaud’s phenomenon). Acrocyanosis. Acroparesthesias. Thrombophlebitis. Disorders of the circulation of the inner ear (primary ischemia of the cochlear cells, spasm of the labyrinthine artery and Ménière’s syndrome). Insuf. Cerebral vascular (characterized by recent memory loss, irritability, anxiety, and insomnia).


Oral: 1 tablet 3-4 times / day (usual therapeutic dose); This dose can be modified between 1/2 – 2 tablets 3-4 times / day according to the severity of the condition and medical criteria.


YO SOY; paroxysmal tachycardia; severe angina pectoris; thyrotoxicosis ; hypothyroidism ; hypersensitivity to bufenin.

Warnings and cautions

It can cause orthostatic hypotension, headache , dizziness and palpitations; in patients with Enf. cardiac such as tachyarrhythmias, insuff. decompensated heart disease and angina pectoris , should be administered under strict medical supervision, as well as in patients with active peptic ulcer.


They have not been described.


The safety of use during pregnancy has not been established, so its use during pregnancy should be under medical supervision, assessing risk-benefit.


It is unknown whether the drug is excreted in human milk.

Adverse reactions

Tremor, nervousness, blurred vision, weakness, vertigo (not associated with labyrinthine artery insufficiency); palpitations, low blood pressure and chest pain; nausea, vomiting, and metallic taste.

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