The buproban , is a drug antidepressant used in the treatment of major depressive disorder and affective disorder stations. The Zyban brand of bupropion is used to help the patient quit smoking by reducing craving and other withdrawal symptoms. Bupropion may also be used for purposes not listed in this medication guide.


This medicine is used together with a support program (such as support group, therapy) to help you stop smoking. The buproban can lessen the symptoms of nicotine withdrawal (eg, irritability, anxiety, restlessness) and nicotine cravings. Quitting smoking lowers your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how buproban works. to reduce the urge to smoke. It may work by restoring the balance of certain natural substances (neurotransmitters) in the brain. Talk to your doctor about the risks and benefits of using this medicine, as well as other methods of quitting smoking (for example, nicotine replacement therapy).

Other uses

This section includes uses of this medicine that are not mentioned in the authorized indications, but that your healthcare professional may advise you. Use this medicine to treat any of the conditions listed in this section only if your healthcare professional has told you to. This medication can also be used to treat mental / mood disorders (eg, depression, attention deficit hyperactivity disorder (DAH), seasonal affective disorder, depressive phase of bipolar disorder). It can also be used to treat binge eating disorder (compulsive overeating).


The buproban is an antidepressant used to treat a variety of conditions including depression and other mental / mood disorders as well as to help you quit smoking. Antidepressants can help prevent suicidal thoughts / attempts and provide other important benefits. However, studies have shown that a small number of people (especially those under the age of 25) who take antidepressants for whatever condition may notice the onset or worsening of depression, other mental / mood symptoms, or suicidal thoughts / attempts . Therefore, it is very important to discuss the risks and benefits of antidepressant medications with your doctor, even if you are not treating a mental / mood condition. Tell your doctor immediately if you notice an onset or worsening of depression / other psychiatric disorders, unusual changes in behavior (including possible suicidal thoughts / attempts), or other mental / mood changes (including the onset or intensification of anxiety, panic attacks, difficulty sleeping, irritability, hostile / angry impulses, impulsive actions, intense restlessness, speaking very fast). Be especially alert for these symptoms when you start treatment with a new antidepressant or when you change the dose. If you are using irritability, hostile / angry impulses, impulsive actions, intense restlessness, speaking very fast). Be especially alert for these symptoms when you start treatment with a new antidepressant or when you change the dose. If you are using irritability, hostile / angry impulses, impulsive actions, intense restlessness, speaking very fast). Be especially alert for these symptoms when you start treatment with a new antidepressant or when you change the dose. If you are using buproban to stop smoking and have any of the above symptoms, stop taking it and contact your doctor immediately. Tell your doctor immediately if you experience any of these side effects after stopping treatment.

How to use

Take this medicine by mouth, usually 2 times a day, with or without food. If it upsets your stomach, take it with food. It is important to take the doses at least 8 hours apart, or as directed by your doctor, to reduce the risk of seizures. When you start treatment with this medicine, you may have difficulty sleeping. Do not take your evening dose too close to bedtime. Do not crush or chew this medicine. Doing so can release all of the drug in one pulse and increase your risk of side effects, including seizures. Also, do not split the pills unless they are marked with a line and instructed to do so by your doctor or pharmacist. Swallow the whole or split tablet without crushing or chewing it. Dosage is based on your medical condition and response to treatment. To minimize side effects, your dose may be increased slowly. Do not take a higher or lower dose than prescribed. Do not take more than 150 milligrams in a single dose. Do not take more than 300 milligrams a day. Taking more than the recommended dose of this medicine may increase your risk of seizures. It is recommended to stop smoking until after taking the buproban for 1 week, to allow drug levels in the blood to be high enough. Set a date to quit smoking, and quit within the second week of taking the medicine. If necessary, you can combine this medicine with nicotine patches or gum to help you quit smoking. For additional information, consult your doctor. Combining nicotine with this medicine can increase your blood pressure. Your doctor may need to closely monitor your blood pressure. Do not smoke once if you are using any nicotine product with this medicine. Using too much nicotine can cause serious side effects. To get the most benefit from this medicine, use it regularly. To help you remember, use it at the same time each day.


Before taking buproban , tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients that can cause allergic reactions or other problems. Consult your pharmacist for more information. Before using this medicine, tell your doctor or pharmacist your medical history, especially of:

  • seizures or conditions that increase your risk of seizures (including brain / head injuries, brain tumors, arteriovenous malformations, eating disorders such as bulimia / anorexia nervosa), alcoholism / drug dependence, diabetes, heart disease (for example, congestive heart failure , recent heart attack), high blood pressure, kidney problems, liver problems (such as cirrhosis), mental / mood disorders (such as bipolar disorder, suicidal thoughts), personal or family history of glaucoma (angle-closure).
  • You should not use this medicine if you are abruptly stopping regular use of sedatives (for example, benzodiazepines such as lorazepam or alcohol, as it will increase your risk of seizures.
  • This medicine may cause dizziness, drowsiness, or blurred vision. Alcohol or marijuana can make you more dizzy or drowsy.
  • Do not drive, use machinery, or do any activity that requires alertness or good vision, until you are sure you can do these activities safely. Avoid drinking alcoholic beverages. Talk to your doctor if you are using marijuana. Alcohol can also increase the risk of having seizures.
  • Do not take this medicine together with any other products that contain buproban (such as antidepressants), as high doses of buproban increase the risk of seizures.
  • Older people may be more sensitive to the side effects of this drug, especially dizziness and forgetfulness.
  • Dizziness can increase the risk of falling.
  • During pregnancy, use this medicine only when clearly needed. Pregnant women who want to quit smoking are encouraged to attend smoking cessation education and behavioral therapy programs.
  • Talk to your doctor about the risks and benefits.
  • This medicine passes into breast milk and may cause unwanted effects in a nursing infant. Consult your doctor before breastfeeding.

Side effects

  • Dizziness
  • Drowsiness.
  • Sickness.
  • Diarrhea.
  • Tiredness.
  • Constipation.
  • blurry vision.
  • increased sweating
  • strange taste in the mouth or stomach pain.

If any of these effects persist or worsen, notify your doctor or pharmacist as soon as possible. Remember that your doctor has prescribed this medicine for you because he or she has determined that the benefit to you is greater than the risk of side effects. Many people using this medicine do not have serious side effects. This medicine can raise your blood pressure. Check your blood pressure regularly and tell your doctor if you get high results. Notify your doctor immediately if any of the following unlikely but serious side effects occur:

  • chest pain.
  • fainting
  • fast / pounding heartbeat, irregular heartbeat, mental / mood changes (such as anxiety, agitation, confusion, forgetfulness), muscle aches, ringing in the ears, severe headache, involuntary movements (tremors), loss or unusual weight gain.

Notify your doctor right away if any of the following rare but very serious side effects occur:

  • muscle pain / tenderness / weakness.

Seek immediate medical attention if you have any very serious side effects, including:

  • eye pain / swelling / redness, dilated pupils, vision changes (for example, seeing rainbows around lights at night).

In rare cases, this drug can cause seizures. Seek immediate medical attention if you have seizures. If you have seizures while taking buproban , you should not take it again. In the unlikely event that you have a very serious allergic reaction to this drug, seek immediate medical attention. Symptoms of a severe allergic reaction include:

  • skin rash, itching / swelling (especially of the face / tongue / throat), severe dizziness, trouble breathing.

Empty pill shells may appear in your stool. This is harmless. This is not a complete list of possible side effects. Contact your doctor or pharmacist if you notice other effects not listed above.


In case of severe overdose symptoms, such as loss of consciousness or breathing difficulties, see your family doctor immediately. Symptoms of an overdose include seizures, severe confusion, hallucinations, a fast heartbeat, and loss of consciousness.


Store this product at room temperature protected from light and moisture. Buproban lozenges can smell strange. This is normal and you can use the medicine. Do not store it in the bathroom. Keep all medicines out of the reach of children and pets. Do not flush medicine down the toilet or drain unless instructed to do so. Properly dispose of this product when the expiration date is reached or when it is no longer needed. Consult your pharmacist or your local waste disposal company.

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